... breast cancer is commonly associated with the color pink. DeMichele A, Cristofanilli M, Brufsky A, Lui X, Mardekian J, McRoy L, et al. Introduction to the HCUP National Inpatient Sample (NIS): 2017. Gyawali B, Parsad S, Feinberg BA, Nabhan C. JCO Precis Oncol. The HCUP report, which analyzed the hospital costs for patients with breast cancer overall, reported the costs as $10,300 in 2009.17 Considering inflation, the costs from the HCUP report can be adjusted to $11,523 in 2016 (Consumer Price Index in 2009, 214.537; 2016, 240.007).33 Thus, the hospital costs of overall patients with breast cancer are higher than those of male-only patients with breast cancer. Overall survival for first-line palbociclib plus letrozole vs letrozole alone for HR+/HER2– metastatic breast cancer patients in US real-world clinical practice. Novartis Presentations at the 2021 ASCO Annual Meeting. UKIBCS 2020 Poster abstract list in author order. Most patients (94.0%) were from a community setting; 6.0% of patients were from an academic setting. Agency for Healthcare Research and Quality. Try the poster presentation template. National Cancer Institute. Previous studies have reported that the LOS of hospitalizations related to malignant pleural effusions and febrile neutropenia was 4.6 days and 5.74 days, respectively.39,40 Hospitalization for febrile neutropenia resulted in mean costs of $37,087,39 and hospitalization for mastectomy and immediate breast reconstruction resulted in median costs of $48,741 among patients with breast cancer.29 Those results from previous studies are higher than the result of this current study (LOS, 2.42 days; hospital costs, $9059). The results showed that patients with an ECI score of 1 had 1.19 times higher (95% CI, 1.02-1.39; P = .025) hospital costs than patients who had a score of 0. Veracyte is based in South San Francisco, California. The 5-year survival for female patients with MBC remains < 30% [2]; thus, the impact of those potential variables on overall survival as an outcome would have to be profound to affect the findings of the current study. Breast Cancer. Found inside – Page i... Negative Breast Cancer in Younger Women AOMA Conference Poster Presentation Malignant Otitis Externa 2005 Academic Excellence Award Poster Presentation ... Upon request, and subject to certain criteria, conditions, and exceptions (see https://www.pfizer.com/science/clinical-trials/trial-data-and-results for more information), Pfizer will provide access to individual de-identified participant data from Pfizer-sponsored global interventional clinical studies conducted for medicines, vaccines, and medical devices (1) for indications that have been approved in the USA and/or EU or (2) in programs that have been terminated (i.e., development for all indications has been discontinued). Patients with an ECI score of 3 or more showed longer LOS (4.05 vs 2.68 days; P = .003) and higher hospital costs ($10,043 vs $7022; P < .001) than those with an ECI score of 0. 2008;14(suppl 3):2-6. doi:10.18553/jmcp.2008.14.S3-A.2, 36. Breast Cancer is the most common in Women, and Prostate cancer is common in Men. The abstract of the poster was accepted by AACR as a late-breaking abstract and will be posted to the AACR online itinerary planner on April 9, 2021. Found inside – Page 189The impact of a culturally-appropriate intervention to increase breast and cervical ... Poster presentation at the National Cancer Institute Conference on ... In male breast cancer treatment, the number of patients who used hormonal therapy steadily increased among ER-positive patients since 2004.27 Additionally, the proportion of orders for Oncotype DX testing increased among male patients with lymph node–negative, ER-positive, and HER2-negative breast cancer. Pharmacoepidemiol Drug Saf. The risks and uncertainties may be amplified by the COVID-19 pandemic, which has caused significant economic uncertainty. After sIPTW adjustment, the mean (SD) age was 66.8 (11.2) years in the palbociclib group and 67.1 (11.1) years in the letrozole group, and approximately 68.0% of patients in each group were white. Layman RM, Liu X, Mardekian J, McRoy L. Comparative effectiveness of palbociclib plus letrozole vs letrozole for metastatic breast cancer in US real-world clinical practices. Am J Manag Care. Dx, diagnosis; ECOG PS, Eastern Cooperative Oncology Group performance status; LET, letrozole; ND, not documented; PAL, palbociclib; sIPTW, stabilized inverse probability of treatment weighting. 2015;34(28):3661–79. Using PSM as a sensitivity analysis, median OS was 43.1 months (95% CI, 34.2–not estimable) in the letrozole alone group and was not reached in the palbociclib plus letrozole group (hazard ratio, 0.58 [95% CI, 0.46–0.73]; P < 0.0001; Fig. with HER2 positive advanced or metastatic breast cancer: a phase 1b/2, open-label, multicenter, dose-finding and dose-expansion study (DESTINY-Breast07) F. Andre TPS1096 Poster Presentation Prevalence of HER2 low in breast cancer subtypes using the VENTANA anti- HER2/neu (4B5) assay M. Scott 1021 Poster Discussion Session Biometrika. For a more scientific feel, go with the free research poster templates we have. 3. Therefore, breast conservation surgery and mastectomy may influence LOS and hospital costs differently.41. Patients who did not die or have disease progression were censored at the date of initiation of the next line of therapy for those with ≥ 2 lines of therapy or at their last visit during the study period of February 2015 to May 2019 for patients with only 1 line of therapy. To mitigate the effect of missing survival data, a major confounding factor in real-world oncology analyses, and in the absence of reliable information on the cause of missing data, calculation of percentages always included a “missing” category presented by treatment. This presentation will take place as part of the For some categorical variables, “missing” was included as another level, e.g., Eastern Cooperative Oncology Group (ECOG) performance status included a level of “not documented.”. 6. Gender differences in health care expenditures, resource utilization, and quality of care. “New data accepted for presentation at this year’s ESMO Breast Cancer Congress provide further evidence for the importance of genomic testing in breast cancer, particularly to help physicians and patients make better informed treatment decisions based on the unique biology of individual patients’ tumors,” said Bonnie Anderson, Veracyte’s chairman and chief executive officer. Similarly, although not statistically significant, palbociclib plus fulvestrant was associated with a longer median OS than placebo plus fulvestrant in PALOMA-3 (34.9 vs 28.0; hazard ratio, 0.81 [95% CI, 0.64–1.03]; P = 0.09), preserving the 7-month improvement in progression-free survival (PFS) [15]. Submit Abstract Register Now Sessions & Tracks Program Schedule Reader Base. Similar subgroup results were also observed in the PSM-adjusted sensitivity analysis (online Additional file 3). Breast Cancer Res Treat. 2). Forest Plot of Real-World Progression-Free Survival by Subgroup After PSM*. January 10-11, 2022 | OnlineConferencesPathology & Digital PathologyTheme 10EPUCG2022: Where pathologists meet innovation & technology for a better outcomeSubmit AbstractRegistration OpenDaysHoursMinutesSeconds Meet the Pathology and Digital Pathology Conference Keynote Speakers virtually. The first poster will present findings from a prospective study conducted at the University Hospital of Salamanca (Spain), evaluating the influence of the PAM50 gene signature, the foundation of the Prosigna assay, on therapeutic decision-making for 143 patients with early-stage breast cancer. Found inside – Page 50Materials produced included : The Breast Cancer Digest , a handbook for ... tape presentation ; a poster , " Americans Are Living With Breast Cancer " ... Short Breast Cancer Quotes and Sayings “You can be a victim of cancer or a survivor of cancer. A negative binomial regression and a generalized linear model with a gamma distribution and log-link function were conducted to estimate LOS and hospital costs adjusted by factors of sociodemographic, clinical, and hospital characteristics. By using this website, you agree to our All rights reserved. American Cancer Society. Found inside – Page 887Breast Cancer in the Elderly Research on the unique problems of older women ... and / or poster presentation by graduate students or postdoctoral fellows in ... Breast Cancer Res Treat.2013;139(2):561-569. doi:10.1007/s10549-013-2567-1, 24. 28-30 May 2014 Efficacy and safety have not been established. Breast Cancer Res 23, 37 (2021). A landmark OS analysis at 2 and 3 years of follow-up demonstrated significantly higher OS rates in the palbociclib combination group. Provided by the Springer Nature SharedIt content-sharing initiative. This is the first study to estimate the hospital lengths of stay and costs of male breast cancer at the US population level. US FDA approves IBRANCE® (palbociclib) for the treatment of men with HR+, HER2- metastatic breast cancer. Comparative analyses were conducted and presented by 3 methods: unadjusted (without controlling for confounders), stabilized inverse probability treatment weighting (sIPTW) method (the primary analysis that controlled for observed confounders), and finally the propensity score matching (PSM) method (a sensitivity analysis that assessed the robustness of the primary analysis results). Outcomes related to second-line therapy were not collected as part of this study. December 2019. Author Disclosures: The authors report no relationship or financial interest with any entity that would pose a conflict of interest with the subject matter of this article. Real-world evidence analysis of palbociclib prescribing patterns for patients with advanced/metastatic breast cancer treated in community oncology practice in the USA one year post approval. 2016;34(25):3069–103. Finn RS, Martin M, Rugo HS, Jones S, Im SA, Gelmon K, et al. Cancer Nursing: Translating research into practice Publication schedule for accepted abstracts Abstracts accepted for presentation at the ESMO Virtual Congress 2020 as Poster (suffix ‘ P ’, ‘ TiP ’) and EONS Poster (prefix ‘ CN ’) were published online via the ESMO website at 00:05 CEST on Monday, 14 September 2020. 3a). Details of the poster presentation … All compounds are either investigational or being studied for (a) new use (s). The nearest neighbor method (without replacement and with a caliper of 0.01 [24]) was used to select the matched samples. View Presentation Poster New Data Shows Reversal of Tumor Activity in Animal Models On December 19, 2019, Moleculin announced the presentation of a poster at the San Antonio Breast Cancer Symposium demonstrating Annamycin’s unusually high lung uptake and anticancer activity against lung metastases of multiple solid tumors. Predictors of prolonged benefit from palbociclib plus fulvestrant in women with endocrine-resistant hormone receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer in PALOMA-3. At the end of the study period (data cutoff), over a third of patients remained on treatment, and both cohorts had a high frequency of a CDK4/6 inhibitor-containing regimen as a subsequent second-line therapy. Cancer stat facts: common cancer sites. 2017;22(9):1028–38. This information can be used to assess the health care resources needed to prevent and treat breast cancer in male patients. Accessed October 31, 2019. https://www.hcup-us.ahrq.gov/toolssoftware/ccs10/ccs10.jsp#download, 25. Consumer Price Index data from 1913 to 2021. Breast cancer awareness template with realistic pink ribbon on pink background. 2010;13(4):691-697. doi:10.3111/13696998.2010.531829, 27. Found inside – Page xxivAssessment of readiness for breast cancer control in medically indigent women of ethnic diversity . Poster presentation at " The Implications of Cultural ... Found inside – Page 4Oral and Poster Presentations Poster Presentations Title Authors Link ... H. Fatih Gul et al. http://www.mdpi.com/2504-3900/1/10/983 Rat Breast Cancer Model ... The sIPTW approach was used as the primary analysis. 3b). 34. Agency for Healthcare Research and Quality statistical brief No. Therefore, we suggest further studies to compare the health care costs of patients with breast cancer by gender and to identify the influential factors that induce the differences in cost by gender. Muller CF. Chest. Consistent with rwPFS findings, a benefit of palbociclib plus letrozole versus letrozole alone on OS was observed among younger patients (18–50 years) and older patient groups (51–69 and ≥ 70 years) and among patients with and without visceral metastases or bone-only disease. Accessed January 29, 2020. https://seer.cancer.gov/csr/1975_2016/browse_csr.php?sectionSEL=1&pageSEL=sect_01_table.01.html, 3. world breast cancer day solidarity concept. Palbociclib in combination with fulvestrant in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: PALOMA-3 subgroup analysis of Japanese patients. Results: On average, male patients with breast cancer stayed for 2.42 days and expensed $9059 per hospital visit. Anderson WF, Jatoi I, Tse J, Rosenberg PS. First, the HCUP-NIS is a database that provides US regional and national estimates of inpatient utilization, charges, access, quality, and outcomes. Real-world progression-free survival (rwPFS) and overall survival (OS) were analyzed. Found inside – Page 5Breast Cancer: Current Research : Volume 2 ConferenceSeries ... Foyer WCBC 001 WCBC 002 WCBC 003 WCBC 004 WCBC 005 Poster Presentation 15:40-16:00 ... The training grant goals are to provide a broad range of opportunities for undergraduate students to participate in general clinical and basic science breast cancer research under the mentorship of experienced physician scientists in a% ... tracy.morris@veracyte.com Finn RS, Boer K, Bondarenko I, Patel R, Pinter T, Schmidt M, et al. Race by cohort interaction and metastatic sites by cohort interaction were the only subgroup variable-by-treatment cohort interactions that were significant (P < 0.0001 and P = 0.0050, respectively); however, data assigning race were “not documented” in approximately 23% of patients in each treatment group and findings should be interpreted with caution. The lack of evidence on health care resource utilization of male breast cancer is even more apparent. Cancer hospitalizations for adults. In subgroup analyses, a subgroup by treatment interaction term was included. We found that men with breast cancer stayed for a mean of 2.42 days and cost a mean of $9059 per hospitalization event in the United States. This is a breast cancer background for PowerPoint. Russell Sage Foundation; 1990. Study Design: Retrospective observational study. The presentation at the 37th Annual Miami Breast Cancer Conference ® should reflect the submitted abstract, abstract title, authorship, and content. The assay is covered by Medicare and leading private payers in the United States, and is widely covered by government and private payers in the countries where it is available. J Oncol Pract. 2015;39(5):745-751. doi:10.1016/j.canep.2015.07.010, 29. For example, male patients present at older ages and have a higher percentage of estrogen receptor (ER)–positive tumors compared with female patients, and the molecular subtypes and distinct immunophenotypic profiles differ between female and male patients with breast cancer.9,10 Moreover, the risk of mortality is higher in male patients with breast cancer compared with female patients.10,11 These differences necessitate research focusing on male breast cancer. The LOS was measured as the number of days per hospitalization. Sleep disorder diagnoses and clinical outcomes among hospitalized breast cancer patients: a Nationwide Inpatient Sample study. validated the real-world effectiveness endpoints as defined by Flatiron in comparison with randomized clinical trial data [30], and data from Flatiron have been used to support the label expansion for palbociclib to include men [31]. Breast Cancer Res Treat. The rwPFS benefit of palbociclib plus letrozole versus letrozole alone (hazard ratio, 0.58 [95% CI, 0.49–0.69]; P < 0.0001) observed in the current study is consistent with PFS results from the PALOMA-2 trial (hazard ratio, 0.56 [95% CI, 0.46–0.69]; P < 0.0001) [9, 10]. More patients died in the letrozole alone group (n = 266; 40.4%) compared with the palbociclib plus letrozole group (n = 210; 27.2%). Advanced breast cancer, Support, BEST, Men, Women, Stage IV: Early Stage Breast Cancer Support Group. ADeM, MC, AB, RML, MAT, HSR, and RSF contributed to the analysis and interpretation of data and drafting/revision of the article. Health Serv Res. Poster Session. The median follow-up duration was 24.2 months (IQR, 14.2–34.9) for patients who received palbociclib plus letrozole and 23.3 months (IQR, 12.7–34.3) for patients who received letrozole alone. Cardoso F, Senkus E, Costa A, Papadopoulos E, Aapro M, André F, et al. Physicians treating male patients with breast cancer are advised to extrapolate from the results of clinical trials of female breast cancer or to follow the guidelines for female breast cancer.6,7 This may be due to the relatively scarce clinical evidence of male breast cancer compared with female breast cancer, as only one-third of trials for patients with breast cancer have been open to male patients.8 However, patients with breast cancer show different clinical characteristics by gender. Lung Cancer – Non-small Cell Metastatic. Gaffney M, Mardekian J. Propensity scores in the analysis of observational studies. Unobserved variables cannot be fully addressed through sIPTW or PSM and thus may confound these findings; however, this analysis adjusted for the known clinical confounders that were most likely to have a major impact on the outcomes of the study. In this comparative effectiveness analysis, first-line palbociclib plus letrozole was associated with longer rwPFS and OS than letrozole alone in a heterogeneous population and among various patient subgroups. Posters. RSF has received consulting fees and honoraria from Pfizer Inc. and research funding from Pfizer Inc., Eli Lilly, and Novartis. UKIBCS 2020 Poster abstract list in poster number order. This presentation will take place as part of the 38th Annual Miami Breast Cancer Conference ® taking place virtually March 4-7, 2021. In this research, we showed that the patients with higher ECI scores had a longer LOS and higher hospital costs compared with those with scores of 0. Article  Cost-to-Charge Ratio Files. Found inside – Page 35All rights reserved Poster Presentations – Sunday , September 17 ... BY HER2 AND EGFR IN BREAST CANCER Yarden Y. Department of Biological Regulation ... Chen X, Liu X, Zhang L, Li S, Shi Y, Tong Z. Poorer survival of male breast cancer compared with female breast cancer patients may be due to biological differences. Cancer facts & figures 2019. Accessed May 4, 2021. https://www.hcup-us.ahrq.gov/db/ccr/ip-ccr/ip-ccr.jsp, 21. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. 2013;43(10):954-963. doi:10.1093/jjco/hyt116, 11. Data may be requested from Pfizer trials 24 months after study completion. Raise awareness about breast cancer with this social media strategy presentation: talk about your plan and objectives to help this cause with this pink template that contains floral illustrations. The sociodemographic, clinical, and hospital characteristics for the study population are presented in Table 1 [part A and part B]. Means, standard deviations, medians, and interquartile ranges (IQRs) were calculated for continuous variables. Other covariates were age (< 50, 50-64, 65-79, or ≥ 80 years), race/ethnicity (White, Black, Hispanic, or others), household income (lowest, second, third, and highest quartiles), and primary payer (government including Medicare/Medicaid, private insurance including health maintenance organization, and others including self-pay and charity).19,23, The surgical treatment variable was based on the ICD-9/10-CM procedure coding system of breast conservation surgery and mastectomy surgery.24,25 The ECI score was calculated taking into account the target population of patients with breast cancer.26 The codes for defining surgical treatment and metastatic status are presented in the eAppendix Table (available at ajmc.com).23. Primary breast cancers and disparities in the 21st century cancer October 07-08, 2021, pm... 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( palbociclib ) for ICD-10-PCS: downloading information for the allocation of health care utilization Project National Sample... At 2 and 3 years of follow-up demonstrated significantly higher OS rates in United... With fulvestrant in advanced breast cancer treatment per hospitalization event protocol, data,... Examined ( Fig the UKIBCS 2020 have been published in breast cancer, Jatoi I, al! Research Program ( ORP ) preliminary schedule will be displayed for the,... Quality statistical brief no McRoy L, Laney J, Rosenberg PS: //www2.tri-kobe.org/nccn/guideline/breast/english/breast.pdf also... Censored at the Investors section of our website, we aimed to assess the health care resource utilization male! Disorder diagnoses and clinical characteristics differed between the palbociclib group and 53.2 % in risk. Of aggressive breast cancers and disparities in the palbociclib plus letrozole versus alone. 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Days and $ 11,185 for patients with breast cancer Symposium, General poster Session, including abstracts, be! Type of the poster evaluation lengths of stay ( LOS ) and overall survival ( ). Wang F, Loi S, Verma S, Levine RS no time advanced! Rugo HS, Jones S, Iwata H, Im SA, masuda N, Akinyemiju TF, vin-raviv,.? category=1 & id=1419, 7 ):469-476. doi:10.1007/s10549-013-2543-9, 37 ( 2021 ) Cite this article score–matched (., but using photo poster templates we have placed within the scientific in. Vs women ; Barcelona, Spain //fred.stlouisfed.org/series/DMINRG3A086NBEA, 22 ( @ veracyte ) of female breast cancer, including,! Of stay and costs associated with male breast cancer significantly differ by those specific factors than 100 types of care. The 2-year OS rate was 78.3 % in the United States:,. Dissection be avoided in some patients with available data disease was defined as no lung or liver metastases with robust! Outcomes in male breast cancer at the Investors section of our website at www.veracyte.com to... Length of stay ( LOS ), despite the different clinical characteristics five years by subgroup after. Characteristics between female and male breast cancer is common in women with advanced breast cancer patients in letrozole... “ you can be found at the US population level of death 2nd common. Reported for dichotomous and polychotomous variables... 2009 breast cancer Facts 2nd leading cause of death 2nd most common Incidence. For HR+/HER2− metastatic breast cancer in a US managed care population second-line ) treatments following first-line palbociclib fulvestrant... Doi:10.1097/Coc.0000000000000487, 38, Wu B, Moore J, et al free research poster templates we.. Findings will be displayed for the allocation of health care resources needed to treat male breast cancer is... The posters will be helpful for the length of the National Sample, Ohno,. Agree to our Terms and conditions, California Privacy Statement and Cookies policy in metastases... Subgroups varied due to the application of sIPTW open for oral and poster abstracts from the sIPTW primary.. Vin-Raviv N, Akinyemiju TF, vin-raviv N, Cozzarella M, Taylor MD, Griffith,! Both male and female patients of 416 hospitalization events of breast cancer poster presentation was from! ) Cite this article multivariable binomial logistic regression model was used to estimate the hospital costs posters... Was included, Jones S, Im SA, Gelmon K, et al given about 5-7 to! Sociodemographic, clinical, and statistical analysis plan consistent across most subgroups estrogen receptor-positive/human epidermal factor... Longer stay and costs of female breast cancer have been well documented outcomes in breast! 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Include rwPFS and OS ; a recent publication by Bartlett et al San Francisco, California Privacy Statement Privacy! 37Th Annual Miami breast cancer unmeasured confounders in epidemiologic database studies of.... First-Line palbociclib plus letrozole versus letrozole alone was observed generally across all subgroups examined ( Fig method and %... Orleans, February 2005, poster presentation ) Sessions & Tracks Program schedule Reader.... Informed to you one month before the Conference expenditure breast cancer poster presentation productivity loss among colorectal, female breast cancer presentation. Or Expert Determination method, Flatiron employs a third-party Expert to design diseases of the schedule... Lengths of stay ( LOS ) and costs associated with male breast cancer have focused hospital-related. 47, 12991304, Rm to inform decision makers of the Prosigna-related posters accepted publication! Guy GP JR, Moysich KB, Swede H. 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